The Karamojong have a unique culture, and they believe that cattle are an indication of royalty; the more cows one has, the more popular they are in their community. The Karamojongs can do anything to maintain the number of their cows.

Karamoja is a semi-arid place where farming is hard, thus creating food scarcity; cultivation is done where possible as a secondary activity in Karamoja. 

Karamojong women are seen as inferior when it comes to culture and norms. Karamojong’s women’s major roles are to stay at home in order to take care of their children and husbands. Karamojong men can be allowed to marry many wives as long as they can afford to pay their dowry. Dowry is a prime factor in Karamoja marriages, paid in the form of cows. 

Karamojong’s families are guided and ruled by elders who make important decisions for them; most families always follow these elders in order to keep their culture alive. And Karamojong's best delicacy is cow’s milk mixed with fresh blood.

The Karamojong men are the ones who rear cattle and build houses, and in the evening, they gather to enjoy a pot of local beer. Karamojong things are done communally, and they share most of the things, such as food and cattle, and they move from place to place in search of water and food for their cattle.

The Karamojong people are known for slaughtering their cattle for ritual purposes, like appeasing Ajuk, their god, or when elders ask for it. Ajuk is appeased for protection against enemies, good health, successful raids, and wealth in different communities.