Tree climbing lions of Ishasha are the big cats of Queen Elizabeth National Park, offering unique experiences in the Ishasha sector located in the southern part of Queen Elizabeth National Park, the second largest national park in Uganda, situated in southwestern Uganda. Queen Elizabeth National Park harbors other animals such as elephants, bushbucks, buffaloes, warthogs, Uganda kobs, waterbucks, giant forest hogs, hippos, antelopes, Nile crocodiles, leopards, hyenas, primates like chimpanzees at Kyambura Gorge, black and white colobus monkeys, red-tailed monkeys, and many bird species.

Queen Elizabeth National Park offers a number of tourism activities where tourists can engage during their safari, such as both morning and evening game drives, lion tracking at the Ishasha sector, a launch cruise at Kazinga Channel, bird watching, nature walks, and chimpanzee trekking at Kyambura Gorge mostly known as the "Valley of the Apes."

Tree-climbing lions in the Ishasha sector can be spotted lazily lying up in acacia or fig tree branches during either a morning or evening game drive in your comfortable 4WD safari vehicle with a knowledgeable driver guide from Devine African Safaris. Other animals spotted include African cape buffaloes, Topi, warthogs, Uganda kobs, elephants, and bird species such as the martial eagle, brown snake eagle, Bateleur, palm nut vulture, Ross's turaco, grey woodpecker, white-headed barbet, African wattled plover, African fish eagle, grey-backed fiscal, white-browed robinchat, broad-billed roller, 

Because of the unique tree-climbing lions, Ishasha Sector is a popular tourist destination for big cat and big five enthusiasts. The Ishasha sector is visited throughout the year, although it is best visited during the dry seasons of June, July, August, September, and December, as well as January, February, and early March each year. During the dry seasons, less rainfall is received, making the roads to the national parks accessible.